Quantitative sonography of basal cell carcinoma
- Resource Type
- Authors
- Andrzej Nowicki; Hanna Piotrzkowska-Wroblewska; Jerzy Litniewski; Elżbieta Szymańska
- Source
- Ultrasound in medicinebiology. 41(3)
- Subject
- Pathology
medicine.medical_specialty
Skin Neoplasms
Acoustics and Ultrasonics
Radiological and Ultrasound Technology
business.industry
Attenuation
Actinic keratosis
Biophysics
Cancer
Human skin
medicine.disease
Carcinoma, Basal Cell
Attenuation coefficient
Carcinoma
medicine
Humans
Radiology, Nuclear Medicine and imaging
Basal cell carcinoma
Skin lesion
business
Ultrasonography
- Language
- ISSN
- 1879-291X
A 30-MHz ultrasonic scanner was used to collect B-scan images together with appropriate radiofrequency echoes from diseased and healthy skin regions of patients with diagnosed basal cell carcinoma and pre-cancerous lesions (actinic keratosis). Radiofrequency data were processed to obtain the attenuation coefficient and statistics of the backscattered echo signal determination (K-distribution and effective density of scatterers [EDS]). The attenuation coefficient was significantly higher for patients with basal cell carcinoma than for healthy patients. Also, the pre-cancerous skin lesions had increased attenuation. The averaged EDS values for cancer lesions were significantly lower than those for pre-cancerous lesions and healthy skin. The successful differentiation between the tissue groups examined suggests the potential value of the attenuation coefficient and EDS for carcinoma characterization.