Sodium multiple quantum spectroscopy of articular cartilage: Effects of mechanical compression
- Resource Type
- Authors
- Umamaheswar Duvvuri; Ravinder Reddy; Jonathan H. Kaufman; Saurabh D. Patel; John S. Leigh; Lizann Bolinger; J. Bruce Kneeland
- Source
- Magnetic Resonance in Medicine. 40:370-375
- Subject
- Cartilage, Articular
Magnetic Resonance Spectroscopy
Materials science
Quantitative Biology::Tissues and Organs
Sodium
Physics::Medical Physics
Analytical chemistry
chemistry.chemical_element
Ion
Weight-Bearing
Nuclear magnetic resonance
Tensile Strength
Quantum system
medicine
Animals
Radiology, Nuclear Medicine and imaging
Spectroscopy
Quantum
Mechanical load
Cartilage
Patella
Compression (physics)
medicine.anatomical_structure
chemistry
Quantum Theory
Cattle
Proteoglycans
Collagen
- Language
- ISSN
- 1522-2594
0740-3194
The effects of mechanical compression on the multiple quantum coherences generated from sodium ions in articular cartilage were investigated. Cartilage samples obtained from bovine patellae were studied during compression at 0.7 MPa (100 psi) for 1 hour. The double quantum filtered spectra showed marked lineshape changes in the compressed samples. Compression did not seem to influence the lineshapes of the single quantum and triple quantum filtered spectra significantly. We found that the residual quadrupolar interaction was reduced in the compressed samples. Changes in the ordering of collagen fibers may be responsible for the observed effect.