DNA Replication Fidelity
- Resource Type
- Authors
- Paula L. Fischhaber; Errol C. Friedberg
- Source
- eLS
- Subject
- Genetics
congenital, hereditary, and neonatal diseases and abnormalities
DNA clamp
integumentary system
biology
Chemistry
DNA polymerase
DNA polymerase II
DNA replication
nutritional and metabolic diseases
Eukaryotic DNA replication
DNA polymerase delta
biology.protein
Primase
Primer (molecular biology)
skin and connective tissue diseases
- Language
DNA polymerases are proteins that catalyse the polymerization of DNA. Fidelity in this process refers to the ability of the polymerase to avoid or to correct errors in the newly synthesized DNA strand. Keywords: DNA polymerase; DNA replication; replicational fidelity; Y family polymerases; xeroderma pigmentosum; mutation