PLATYPNEA-ORTHODEOXIA SYNDROME: KEY PATHOGENETIC ROLE OF PATENT FORAMEN OVALE (PFO) AND DRAMATIC RESPONSE TO PFO CLOSURE
- Resource Type
- Authors
- Nicholas Collins; David S. Celermajer; David Tanous; Edmund M.T. Lau; Rachael Cordina; Karan Rao; Farrah Othman; Brian P. Bailey
- Source
- Journal of the American College of Cardiology. 75:1204
- Subject
- medicine.medical_specialty
business.industry
Central venous pressure
medicine.disease
respiratory tract diseases
Shunting
Pfo closure
Internal medicine
Patent foramen ovale
medicine
Cardiology
sense organs
In degree
skin and connective tissue diseases
Cardiology and Cardiovascular Medicine
business
Platypnea orthodeoxia
- Language
- ISSN
- 0735-1097
PFO-associated platypnea-orthodeoxia syndrome (POS) is characterised by dyspnoea and hypoxaemia when upright. The pathogenesis is thought to involve an increase in right atrial pressure or change in degree of right to left shunting with upright posture due to structural change. We sought to