International audience; In order to reduce the volume and the radiotoxicityof the nuclear waste coming from the operation of existingpressurized water reactors, accelerator-driven systems(ADSs) have been envisioned.The Helium-cooled (He) European Facility forIndustrial-scale Transmutation (He-EFIT) concept is theEUROpean Research Programme for the TRANSmutationof High Level Nuclear Waste in Accelerator DrivenSystem (EUROTRANS) Integrated Project (IP) (EUROTRANSIP) backup option, whereas Pb-cooled EFITis the reference one. The plant has a power of ;400MW(thermal). Like all ADS plants, it consists of threemain components: the accelerator, the spallation targetmodule, and the subcritical core.This paper describes the He-EFIT design at the endof the EUROTRANS IP as well as the studies performedto support this design: spallation performances, trasmutationcapabilities, and plant safety analyses.No specific technology deadlock has been identified,and it might be possible to build such a plant given necessaryresearch and development in support.