Effects of high-intensity interval training and flaxseed oil supplement on learning, memory and immobility: relationship with BDNF and TrkB genes
- Resource Type
- Authors
- Saleh Rahmati-Ahmadabad; Mohammad Nasehi; David Broom; Mohammad Ali Azarbayjani
- Source
- Comparative Exercise Physiology. 17:273-283
- Subject
- 0301 basic medicine
medicine.medical_specialty
Physiology
Veterinary (miscellaneous)
Endocrinology, Diabetes and Metabolism
Biophysics
Tropomyosin receptor kinase B
Biochemistry
Interval training
03 medical and health sciences
0302 clinical medicine
Physiology (medical)
Internal medicine
medicine
Orthopedics and Sports Medicine
Learning memory
Gene
business.industry
Cognition
Executive functions
030104 developmental biology
Endocrinology
TYROSINE KINASE RECEPTOR B
business
High-intensity interval training
030217 neurology & neurosurgery
- Language
- ISSN
- 1755-2559
1755-2540
This study examined the independent and combined effects of high-intensity interval training (HIIT) and flaxseed oil supplementation on cognitive/executive functions in middle-aged rats. Hippocampal neurotropic brain factor (BDNF) and tyrosine kinase receptor B (TrkB) gene expression were also measured. Animals were randomly divided into groups including no exercise control and saline (CS), no exercise control and flaxseed oil supplement (CF), exercise training-and saline (TS) and exercise training and flaxseed oil supplement (TF). The training groups undertook a program of HIIT (10 weeks, five sessions per week) and the supplement groups received flaxseed oil supplement (300 mg/kg). The results showed that HIIT and flaxseed oil supplementation independently had positive effects on memory and learning (P