Additional file 4: Figure S4. Change in TILs percentage overall; CD4+ and CD8+ TILs counts in primary site and bone metastasis; CD68+ and HLA-DR+ Macrophages counts in primary site and bone metastasis; PD-1 and PD-L1 positive percentage in primary site and bone metastasis in Luminal type, HER2 positive type and triple negative type breast cancer.