Prostatic abscesses and severe sepsis due to methicillin-susceptible Staphylococcus aureusproducing Panton-Valentine leukocidin
- Resource Type
- Authors
- Bruno François; Yannis Brakbi; Anne Cypierre; Frédéric Laurent; Maria Dubos; Anne-Laure Fedou; Fabien Fredon; Olivier Barraud
- Source
- BMC Infectious Diseases
- Subject
- Male
Staphylococcus aureus
Ofloxacin
medicine.medical_specialty
Pathology
Bacterial Toxins
Exotoxins
Prostatitis
Case Report
Fosfomycin
medicine.disease_cause
Gastroenterology
Methicillin
Young Adult
Panton-valentine leukocidin
Leukocidins
Sepsis
Internal medicine
medicine
Humans
Ultrasonography
Prostatic abscess
Urinary retention
business.industry
Soft Tissue Infections
Staphylococcal Infections
biochemical phenomena, metabolism, and nutrition
bacterial infections and mycoses
medicine.disease
Magnetic Resonance Imaging
Severe sepsis
Abscess
Infectious Diseases
Amikacin
Ceftriaxone
medicine.symptom
Panton–Valentine leukocidin
Tomography, X-Ray Computed
Methicillin Susceptible Staphylococcus Aureus
business
medicine.drug
- Language
- ISSN
- 1471-2334
Background Prostatic abscesses are an uncommon disease usually caused by enterobacteria. They mostly occur in immunodeficient patients. It is thus extremely rare to have a Staphylococcal prostatic abscess in a young immunocompetent patient. Case presentation A 20-year-old patient was treated with ofloxacin for a suspicion of prostatitis. An ultrasonography was performed because of persisting symptoms and showed acute urinary retention and prostatic abscesses. So the empirical antibiotic therapy was modified with ceftriaxone/amikacin. The disease worsened to severe sepsis and the patient was admitted in ICU. CT-scan and MRI confirmed three abscesses with perirectal infiltration and the bacteriological samples (abscesses and blood cultures) were positive to methicillin-susceptible Staphylococcus aureus producing Panton-Valentine leukocidine. The treatment was changed with fosfomycin/ofloxacin which resulted in a general improvement and the regression of the abscesses. Conclusion Staphyloccocus aureus producing Panton-Valentine leukocidin are most commonly responsible for skin and soft tissue infections. To this day, no other case of prostatic abscess due to this strain but susceptible to methicillin has been described. Electronic supplementary material The online version of this article (doi:10.1186/1471-2334-14-466) contains supplementary material, which is available to authorized users.