Idiotype/anti-idiotype antibodies: as a glorious savior in COVID-19 pandemics
- Resource Type
- Authors
- Sajjad Ur Rahman; Ahsan Naveed; Deeba Naz
- Source
- Translational Medicine Communications
Translational Medicine Communications, Vol 6, Iss 1, Pp 1-5 (2021)
- Subject
- Idiotype
biology
Coronavirus disease 2019 (COVID-19)
business.industry
COVID-19
Outbreak
SARS-2
Review
General Medicine
Immune system
Antigen
Polyclonal antibodies
Pandemic
Immunology
Anti-idiotype
biology.protein
Medicine
Antibody
business
Vaccine
- Language
- ISSN
- 2396-832X
The idiotype network is experimentally modified to provide protective immunity against various microbial pathogens. Both internal and non-internal image-idiotype antibodies can trigger specific immune responses to antigens. The current outbreak of Severe Acute Respiratory Syndrome 2 (SARS-2) has provided a great opportunity to take advantage of idiotype / anti-idiotype antibodies as a protective regimen when no approved vaccine is available on earth. The current review identifies successful applications of idiotype/ anti-idiotype antibodies in various viral diseases and highlights their importance in COVID-19 pandemics. In the absence of vaccines and targeted therapies, polyclonal idiotype/ anti-idiotype antibodies against the viral structure may be a potential approach to the prevention and treatment of COVID-19 patients.