Natural history of subfoveal pigment epithelial detachments associated with subfoveal or unidentifiable choroidal neovascularization complicating age-related macular degeneration
- Resource Type
- Authors
- Lawrence J. Singerman; Jeffrey H. Stockfish
- Source
- Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 227(6)
- Subject
- Male
medicine.medical_specialty
Aging
Fovea Centralis
Visual acuity
genetic structures
Visual Acuity
Neovascularization
Cellular and Molecular Neuroscience
Macular Degeneration
Risk Factors
Ophthalmology
medicine
Humans
Life Tables
Macula Lutea
Fluorescein Angiography
Pigment Epithelium of Eye
Aged
Aged, 80 and over
medicine.diagnostic_test
Neovascularization, Pathologic
business.industry
Choroid
Retinal Detachment
Retinal detachment
Macular degeneration
Middle Aged
medicine.disease
Fluorescein angiography
Prognosis
eye diseases
Sensory Systems
medicine.anatomical_structure
Choroidal neovascularization
Female
sense organs
medicine.symptom
business
Retinopathy
- Language
- ISSN
- 0721-832X
There have been few studies of the natural history of pigment epithelial detachments associated with choroidal neovascularization, and none confined to subfoveal lesions. We studied the natural history of 55 eyes in 53 patients who had age-related macular degeneration and subfoveal pigment epithelial detachment associated with choroidal neovascularization that was subfoveal or unidentifiable in location. Life table analysis showed that, at 1-year follow-up, 65% had a visual acuity less than 20/200 and 26% had less than 5/200. Age was a significant risk factor for reduction in both initial and final visual acuity. The presence of both hemorrhage and exudate on initial presentation was a significant risk factor for poor initial visual acuity.