Noninvasive Tracking of Implanted Cells: Superparamagnetic Iron Oxide Nanoparticles as a Long-Term, Multimodal Imaging Label
- Resource Type
- Authors
- Mughil, Sriramvenugopal; Christina A, Pacak
- Source
- Methods in molecular biology (Clifton, N.J.). 2126
- Subject
- Myoblasts
Mice
Animals, Newborn
Cell Tracking
Animals
Contrast Media
Heart
Magnetic Iron Oxide Nanoparticles
X-Ray Microtomography
Magnetic Resonance Imaging
Multimodal Imaging
- Language
- ISSN
- 1940-6029
Superparamagnetic iron oxide (SPIO) nanoparticles can function as specific, long-term multimodal contrast agents for noninvasive imaging studies. Here we describe how to achieve high-resolution, long-term, serial images of single-label transplanted cells through two complementary imaging techniques: magnetic resonance imaging (MRI) and microcomputed tomography (μCT).