Proof of Therapeutic Efficacy of a
- Resource Type
- Authors
- Jörg, Schulz; Martin, Rohracker; Marvin, Stiebler; Jürgen, Goldschmidt; Franziska, Stöber; Mercedes, Noriega; Anette, Pethe; Mathias, Lukas; Frank, Osterkamp; Ulrich, Reineke; Aileen, Höhne; Christiane, Smerling; Holger, Amthauer
- Source
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(6)
- Subject
- Mice, Nude
Reproducibility of Results
Apoptosis
Lutetium
Sensitivity and Specificity
Theranostic Nanomedicine
Mice
Treatment Outcome
Cell Line, Tumor
Colonic Neoplasms
Animals
Humans
Receptors, Neurotensin
Female
Molecular Targeted Therapy
Radiopharmaceuticals
HT29 Cells
- Language
- ISSN
- 1535-5667
Increased expression of neurotensin receptor 1 (NTR1) has been shown in a large number of tumor entities such as pancreatic or colon carcinoma. Hence, this receptor is a promising target for diagnostic imaging and radioligand therapy. Using the favorable biodistribution data of the NTR1-targeting agent