MicroRNA-151 regulates the growth, drug sensitivity and epithelial mesenchymal transition of human glioma cells by targeting profilin 2
- Resource Type
- Authors
- Wenxue Zhang; Hanhong Niu; Rongze Wang; Chenchao Liu; Yi Wang
- Source
- Acta biochimica Polonica. 69(1)
- Subject
- Adult
Male
Epithelial-Mesenchymal Transition
Carcinogenesis
Down-Regulation
Glioma
Cadherins
General Biochemistry, Genetics and Molecular Biology
Up-Regulation
MicroRNAs
Profilins
Cell Movement
Doxorubicin
Cell Line, Tumor
Humans
Female
Cell Proliferation
- Language
- ISSN
- 1734-154X
The microRNA-151 (miR-151) has been reported to be involved in the growth, development, and tumorigenesis of different types of human cancers. This study was designed to unravel the role and therapeutic potential of miR-151 in glioma. The results showed glioma was found to be associated with significant (P