Isolation, Characterization, and Antimicrobial Activity of Extracellular Polypeptides from Diazotrophic Strain Rhizobium radiobacter
- Resource Type
- Authors
- A. Waili; Abulimiti Yili; Haji Akber Aisa; Parhat Rozi; Bakhtiyor A. Rasulov; Yanhua Gao; Yasen Mijiti
- Source
- Chemistry of Natural Compounds. 54:330-333
- Subject
- 0301 basic medicine
chemistry.chemical_classification
Strain (chemistry)
biology
030106 microbiology
Peptide
Plant Science
General Chemistry
medicine.disease_cause
biology.organism_classification
Antimicrobial
General Biochemistry, Genetics and Molecular Biology
Microbiology
03 medical and health sciences
030104 developmental biology
chemistry
medicine
Extracellular
Rhizobium
Diazotroph
Candida albicans
Escherichia coli
- Language
- ISSN
- 1573-8388
0009-3130
Antimicrobial polypeptide fractions were isolated from Rhizobium radiobacter culture medium and purified. Mass-spectrometric analysis showed that the most active biocidal peptide fraction contained 24 components with molecular masses in the range 1171.14–3626.78 Da. The isolated peptide fractions contained 60 and 56% protein, respectively, and inhibited the growth of test pathogens Candida albicans (CA) and Escherichia coli (EC). These polypeptides demonstrated protective properties.