Use of stem cells and growth factors in rotator cuff tendon repair
- Resource Type
- Authors
- Dimitrios Tsekes; Daniel Rossouw; Jagwant Singh; Georgios Konstantopoulos; Mike Elvey; Wasim S. Khan
- Source
- European journal of orthopaedic surgerytraumatology : orthopedie traumatologie. 29(4)
- Subject
- Surgical repair
Platelet-Derived Growth Factor
medicine.medical_specialty
business.industry
Platelet-Rich Plasma
Mesenchymal Stem Cell Transplantation
Surgery
Tendon
Rotator Cuff Injuries
Fibroblast Growth Factors
medicine.anatomical_structure
Age groups
Transforming Growth Factors
Bone Morphogenetic Proteins
Granulocyte Colony-Stimulating Factor
Medicine
Tears
Animals
Humans
Orthopedics and Sports Medicine
In patient
Rotator cuff
Stem cell
business
- Language
- ISSN
- 1432-1068
The management of rotator cuff tears continues to prove challenging for orthopaedic surgeons. Such tears affect most age groups and can lead to significant morbidity in patients. The aetiology of these tears is likely to be multifactorial; however, an understanding of the mechanisms involved is still under review. Despite advancements in surgical operative techniques and the materials used, post-operative recurrence rates after surgical repair remain high. A growing area of research surrounds biological adjuncts used to improve the healing potential of the repaired tissues. This review of recent publications focuses on the strengths and limitations of using stem cells and growth factors in rotator cuff repair.