Characterization of peripheral T helper 17 (Th17) cells phenotype in postmenopausal women with estrogen insufficiency
- Resource Type
- Authors
- Hetal Bhadricha; Vainav Patel; Anushree Patil; Suchitra Surve; Meena Desai
- Source
- Blood cells, moleculesdiseases. 98
- Subject
- Postmenopause
Mice
Phenotype
Molecular Medicine
Animals
Th17 Cells
Female
Estrogens
Cell Biology
Hematology
Th1 Cells
Molecular Biology
- Language
- ISSN
- 1096-0961
Over the past few years, Th17 cells is considered a key player in osteoporosis pathogenesis. Although extensively studied in murine models, comprehensive Th17 cell characterization in osteoporotic women is elusive. We thus aimed to examine peripheral Th17 cells frequency and phenotypes in healthy and osteoporotic women. Our results demonstrated that Th17 cells were primarily CD4