Additional file 1: Fig. S1. Gating strategy of mucosal-associated invariant T (MAIT) cells. Fig. S2. Correlation analysis of mucosal-associated invariant T (MAIT) cell frequencies with CD4+ T-cell counts (a), plasma human immunodeficiency virus (HIV) viral load (b) and the frequencies of CD38highHLA-DR+-expressing MAIT cells (c). Fig. S3. Workflow and quality-control of scRNA-seq. Fig. S4. Increased mucosal-associated invariant T (MAIT) cells in colorectal mucosa tissues from human immunodeficiency virus type 1 (HIV-1) infected patients.