In order to research the influence of homogeneity on the rockburst tendency and on AE characteristics of coal-rock combination body, uniaxial compressive tests of inhomogeneous coal-rock combination bodies obeyed by the Weibull distribution were simulated using particle flow code (PFC2D). Macromechanical properties, energy evolution law, and AE characteristics were analyzed. The results show that (1) the elastic modulus homogeneitymEhas an exponential relation with macroscopic modulusE, and the bonding strength homogeneitymσhas an exponential relation with uniaxial compressive strengthσc; (2) the rockburst tendency of the coal-rock combination body will increase with the increase ofmEormσ, andmσis the leading factor influencing this tendency; and (3) both the change law of AE hits and lasting time in different periods of AE characteristics are influenced bymσ, butmEjust influences the lasting time. The more inhomogeneous the coal-rock combination body is, the shorter the lasting time in booming period of AE characteristics will be. This phenomenon can be used to predict the rockburst tendency of the coal-rock combination body.