Engineering a multi-target therapy nanoplatform against tumor growth and metastasis
- Resource Type
- Authors
- Di, Zhang; Jing, Nie; Dongbo, Wang; Huina, Wu; Lei, Sun; Xuejian, Wang; Jiyong, Wu
- Source
- Chemical communications (Cambridge, England). 58(23)
- Subject
- Cell Line, Tumor
Neoplasms
Anti-Inflammatory Agents, Non-Steroidal
Humans
Antineoplastic Agents
Prodrugs
Cisplatin
- Language
- ISSN
- 1364-548X
Tumor growth and metastasis are caused by many factors. The complexity means that a multi-target combination therapy strategy should be selected against tumor growth and metastasis. Here, cisplatin (CDDP) and bendazac (Ben) were designed as a novel NSAID-Pt(IV) nanoplatform, which is an effective weapon for combating tumor growth and metastasis.