Mn–Fe layered double hydroxide nanosheets: a new photothermal nanocarrier for O2-evolving phototherapy
- Resource Type
- Authors
- Chao Wang; Yudi Ruan; Wenyao Zhen; Xiaodai Jia; Xiue Jiang
- Source
- Chemical Communications. 54:11729-11732
- Subject
- Hyperthermia
medicine.medical_treatment
Photodynamic therapy
02 engineering and technology
010402 general chemistry
01 natural sciences
Catalysis
chemistry.chemical_compound
Materials Chemistry
medicine
Photosensitizer
Tumor hypoxia
Chemistry
Metals and Alloys
General Chemistry
Photothermal therapy
021001 nanoscience & nanotechnology
medicine.disease
Tumor tissue
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Biophysics
Hydroxide
Nanocarriers
0210 nano-technology
- Language
- ISSN
- 1364-548X
1359-7345
Iron–manganese layered double hydroxide nanosheets were developed as an effective photothermal nanocarrier for loading a photosensitizer. The catalase-like activity enables the nanosheets to decompose H2O2 into O2, overcoming tumor hypoxia and enhancing O2-dependent photodynamic therapy (PDT). The combination of PDT and photothermal therapy (PTT) can almost completely eliminate tumor tissues.