Open PHACTS started as an Innovative Medicines Initiative (IMI) project in 2011. The objective was to integrate a wide range of pharmacologically related data into a central resource that is described according to standards of the semantic web community. Central to this unification was the development of an API to allow the project partners to build their own custom applications and workstreams. Also central to the Open PHACTS Discovery Platform is the development of identity resolution and identity mapping services and a chemistry resolution service. Over the last year the Open PHACTS Discovery Platform has matured with many exciting improvements and greater sustainability of the platform, improved code, data updates and new data sources.