Tear film break-up time evaluation by real-time wavefront aberrometry in adult patients with meibomian gland
- Resource Type
- Authors
- L Dupont; Pj Pisella; Dominique Bremond-Gignac; W Zakari; Jj Gicquel; M Djabarouti
- Source
- Acta Ophthalmologica. 90
- Subject
- medicine.medical_specialty
Reproducibility
Adult patients
business.industry
Meibomian gland
Wavefront aberrometry
General Medicine
Tear film break-up time
eye diseases
Pupil
Surgery
Ophthalmology
medicine.anatomical_structure
Aberrometry
medicine
In patient
sense organs
business
- Language
- ISSN
- 1755-375X
Purpose To evaluate tear break-up time (BUT) with repeated higher order wavefront aberrations (HOA) measurements in adult patients with Meibomian Gland Dysfunction(MGD). Methods Wavefront aberrations up to the sixth order for a 4-mm pupil were measured in 10 normal subjects (Group 1) and 10 patients with severe MGD (Group 2) with corneal involvement, using the IRX3 (Imagine Eyes, Orsay, France) Hartmann-Shack (H-S) aberrometer. The aberrometry was performed once every second for up to 20 seconds. HOA measurements were performed 3 times in a row. HOA variations were compared with the BUT by the conventional fluorescein method(CFM). Results There was an excellent correlation between the HOA variation and the BUT recorded by the CFM in both groups. There was also an excellent reproducibility of the HOA measurements in all patients. BUT was significantly decreased (P