Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
- Resource Type
- Authors
- Robert F. Miller; Victoria Johnston; Eliza Gil; Veronica Barrett; Michael Brown; Stephen Morris-Jones; Nicola Sweeney
- Source
- Emerging Infectious Diseases, Vol 27, Iss 3, Pp 944-948 (2021)
Emerging Infectious Diseases
- Subject
- nontuberculous mycobacteria
Epidemiology
lcsh:Medicine
HIV Infections
Mycobacterium abscessus
Antimycobacterial
chemistry.chemical_compound
antitubercular drugs
0302 clinical medicine
030212 general & internal medicine
Diarylquinolines
bedaquiline
bacteria
Mycobacteriaceae
biology
Coinfection
Dispatch
Infectious Diseases
antiinfective drugs
NTM
Microbiology (medical)
Combination therapy
medicine.drug_class
18fluorodeoxyglucose-positron emission tomography/computed tomography imaging
030231 tropical medicine
Mycobacterium Infections, Nontuberculous
Microbiology
Mycobacterium
lcsh:Infectious and parasitic diseases
respiratory infections
03 medical and health sciences
co-infection
Antibiotic resistance
medicine
Humans
viruses
lcsh:RC109-216
antimicrobial resistance
Adverse effect
antibacterial drugs
business.industry
lcsh:R
HIV
biology.organism_classification
tuberculosis and other mycobacteria
chemistry
Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
Nontuberculous mycobacteria
Bedaquiline
business
Mycobacterium avium
- Language
- English
- ISSN
- 1080-6059
1080-6040
Nontuberculous mycobacteria can cause disseminated infections in immunocompromised patients and are challenging to treat because of antimicrobial resistance and adverse effects of prolonged multidrug treatment. We report successful treatment with bedaquiline, a novel antimycobacterial drug, as part of combination therapy for 2 patients with disseminated nontuberculous mycobacteria co-infected with HIV.