Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients
- Resource Type
- Authors
- Tommaso Galeotti; Emiliano Panieri; Maurizio Martini; Anna Maria Ferrara; Luigi Maria Larocca; Katherine A. Siminovitch; Manuela Giachelia; Giovambattista Pani
- Source
- Inflammatory Bowel Diseases. 18:439-448
- Subject
- Male
medicine.medical_specialty
Organic Cation Transport Proteins
Colorectal cancer
IBD
SNP
Ulcerative
Single-nucleotide polymorphism
Polymorphism, Single Nucleotide
Gastroenterology
Inflammatory bowel disease
Statistics, Nonparametric
Pathogenesis
Settore MED/04 - PATOLOGIA GENERALE
Internal medicine
Genotype
Carcinoma
Humans
Immunology and Allergy
Medicine
RNA, Messenger
Colitis
Solute Carrier Family 22 Member 5
Inflammation
Chi-Square Distribution
Settore MED/08 - ANATOMIA PATOLOGICA
Symporters
business.industry
Interleukin-8
NF-kappa B
OCTN1-2
Middle Aged
Octn1
medicine.disease
Ulcerative colitis
Cell Transformation, Neoplastic
Immunology
Disease Progression
Colitis, Ulcerative
Female
Caco-2 Cells
Colorectal Neoplasms
business
- Language
- ISSN
- 1078-0998
Background: Ulcerative colitis (UC) is associated with colorectal cancer. Chronic inflammation may also play a role in the pathogenesis of sporadic colorectal cancer (SCC), particularly in younger patients (