[A Case of Local Recurrence of Bile Duct Cancer Completely Responding to Chemoradiotherapy with S-1]
- Resource Type
- Authors
- Keigo, Yamamichi; Hiroyuki, Sueyoshi; Yoshito, Tanaka; Tatsuma, Sakaguchi; Hidehiko, Hishikawa; Aiko, Ueda; Takashi, Matsuura; Takashi, Ozaki; Takuya, Saito
- Source
- Gan to kagaku ryoho. Cancerchemotherapy. 42(12)
- Subject
- Aged, 80 and over
Male
Antimetabolites, Antineoplastic
Drug Combinations
Oxonic Acid
Bile Duct Neoplasms
Recurrence
Humans
Chemoradiotherapy
Pancreaticoduodenectomy
Tegafur
- Language
- ISSN
- 0385-0684
An 80-year-old man with common bile duct cancer was treated by pancreaticoduodenectomy with D2 lymph node dissection in October 2005. The patient presented with frequent episodes of bloody-mucous rectal discharge in July 2009. An abdominal CT demonstrated local recurrence at the hepatoduodenal ligament. We treated him with concurrent chemoradiotherapy (CRT) with single-dose S-1 chemotherapy. After 6 months, we diagnosed a complete response (CR) by follow-up CT. The patient was treated with S-1 for 3 years after the diagnosis of a CR. He is alive without disease 6 years after the diagnosis of the recurrence. Concurrent CRT with S-1 chemotherapy may be the therapy of choice for recurrence of bile duct cancer.