Perioperative outcomes and survival in elderly patients aged ≥ 75 years undergoing gastrectomy for gastric cancer: an 18-year retrospective analysis in a single Western centre
- Resource Type
- Authors
- Susanna Lam; Charbel Sandroussi; David Storey; Shew Phyo Han; Elinor Tan
- Source
- Langenbeck's Archives of Surgery. 406:1057-1069
- Subject
- medicine.medical_specialty
business.industry
Lymphovascular invasion
medicine.medical_treatment
Perioperative
humanities
03 medical and health sciences
0302 clinical medicine
Cardiothoracic surgery
030220 oncology & carcinogenesis
Internal medicine
Cohort
Propensity score matching
Medicine
030211 gastroenterology & hepatology
Surgery
Gastrectomy
business
Contraindication
Abdominal surgery
- Language
- ISSN
- 1435-2451
1435-2443
Surgical resection for elderly patients with gastric cancer is controversial. This study aims to evaluate the preoperative features and postoperative short- and long-term outcomes of elderly patients following surgical resection for gastric adenocarcinoma. Between January 2000 and May 2018, a total of 177 consecutive patients underwent curative gastrectomy for gastric adenocarcinoma was retrospectively reviewed. Propensity score matching (PSM) analysis was used to balance confounding covariates between the elderly and non-elderly groups. Clinicopathological characteristics, intraoperative characteristics, postoperative complications and long-term survival outcomes including overall survival (OS) and Disease Specific Survival (DSS) were compared and analysed using the Kaplan-Meier log-rank test. Multivariate cox proportional hazards regression analysis of clinicopathological factors influencing survival were evaluated. There were 50 patients in the elderly group (age ≥ 75 years) and 127 patients in the non-elderly group (age