This study included 151 patients and compared four techniques for appendectomy specimen removal during laparoscopy in a tertiary health centre. An endo bag was the most common removal technique which is preferred in the elderly, whereas, direct removal is preferred in younger patients (p=0.045). A lower median CRP level was observed in the powdered glove group (p=0.025), and median values of hospital stay were longer in powder-free and powdered glove groups (p0.001). In comparing the powder-free glove group and powdered glove group, there was only a difference in median hospital stays, and the median level was higher in the powdered glove group. The present study's results show direct removal is the best method because of the reduced need for catheters during surgery and the short hospital stay. However, powdered gloves technique is preferred method in cases with less inflammation, though, it prolongs the need for drainage catheter use and length of hospital stay. Therefore, we emphasise that removal via powdered gloves is the worst technique among the four techniques. Key Words: Appendectomy, Appendicitis, Laparoscopy, Morbidity, Readmission.