At the onset, we must applaud the vision of the editorial board of The Open Dentistry Journal (TODENT J), and the publisher, Ms. Ajum Ara at Bentham Science, for realizing a special issue on evidence-based dentistry (EBD). It is a momentous occasion because it launches the second decade of the field: in fact, it was in 1999, that the American Dental Association (ADA) first made the pronouncement that EBD entailed the judicious integration of recommendations derived from the best available evidence, together with the dentist expertise, the patient’s wants & needs, laboratory tests and X-rays, and insurance coverage and other financial limitations, in order to reach a diagnosis, develop and treatment plan, and follow-up its outcomes.