Acute Myeloid Leukemia Presenting with Numb Chin Syndrome: A Case Report and Review of Literature
- Resource Type
- Authors
- Mohamed A. Yassin; Mohamed Abdelrazek; Shehab F. Mohamed; Deena Mudawi; Mona M Babikir; Abdulqadir J. Nashwan; Saleema C. Purayil; Khalid E. Ahmed
- Source
- The American Journal of Case Reports
- Subject
- Adult
Male
Chin
medicine.medical_specialty
Myeloid
Anthracycline
030204 cardiovascular system & hematology
Hemoglobin gm/dL (normal range: 13.0–17.0 mg/dL)
Hypesthesia
03 medical and health sciences
0302 clinical medicine
Antineoplastic Combined Chemotherapy Protocols
medicine
Humans
Paresthesia
WBC 103/μL (normal range: 4.0–10×103/μL)
Trigeminal nerve
business.industry
platelet 103 μL (normal range: 150–400×103/μL)
Myeloid leukemia
Syndrome
Articles
General Medicine
Hypoesthesia
medicine.disease
Dermatology
Leukemia, Myeloid, Acute
Leukemia
medicine.anatomical_structure
030220 oncology & carcinogenesis
Cytarabine
medicine.symptom
business
medicine.drug
- Language
- ISSN
- 1941-5923
Patient: Male, 30-year-old Final Diagnosis: Acute myeloid leukemia Symptoms: Jaw numbness and pain Medication:— Clinical Procedure: None Specialty: Hematology Objective: Rare co-existance of disease or pathology Background: Numb chin syndrome is a rare and under diagnosed neuropathy of the inferior alveolar branch of the trigeminal nerve usually causing a lower lip and chin anesthesia or paresthesia. The syndrome is commonly associated with broad-spectrum malignant and non-malignant conditions. Case Report: Here we report a case of a 30-year-old male who presented with numb chin syndrome in the form of jaw pain, paresthesia, and hypoesthesia of the mental area as the presenting symptoms of acute of myeloid leukemia with t(8;21) treated with (3+7) protocol (3 days anthracycline+7 days cytarabine). The pain and paresthesia improved but hypothesia persisted. Conclusions: Acute myeloid leukemia is one of the most serious causes of numb chin syndrome which should not be overlooked.