Background: Although the widespread private use of household cleaning agents and disinfectants may have an influence on asthma prevalence, there is only limited evidence in young adults. Aims and Objectives: To investigate the potential association of asthma prevalence in young adults with private use of household cleaning sprays and disinfectants including frequency of use and type of exposure. Methods: We analysed cross-sectional data from a sample of 1671 young adults (response rate: 55.6%) aged 19 to 24 years who were recruited for the Study on Occupational Allergy Risks (SOLAR). Using logistic regression models, odds ratios (OR) and 95% confidence intervals (95% CI) were calculated with adjustment for the potential confounders sex, age, socio-economic status, study location, smoking status and occupational exposure to disinfectants. Results: After adjustment for confounders, participants using disinfectants on less than one day per week (OR: 2.17, 95 % CI: 1.30 – 3.60) and between one to three days per week (OR: 2.86, 95% CI: 1.34 – 6.12) had higher odds of asthma compared to those participants not using disinfectants at all. We did not observe an association between use of cleaning sprays and asthma prevalence. We were unable to attribute increased prevalence of asthma to a specific type of household cleaning spray or disinfectant. Conclusions: Our results support the hypothesis that the use of disinfectants is associated with an increased risk of having asthma. The role of specific sprays and disinfectants needs further clarification.