Controlled Clinical Trial of Clofazimine in Untreated Lepromatous Leprosy*
- Resource Type
- Authors
- S. Karat; Anbu Jeevaratnam; A. B. A. Karat; P. S. S. Rao
- Source
- Subject
- Adult
medicine.medical_specialty
Anti-Inflammatory Agents
Drug resistance
Dapsone
Clofazimine
Erythema Nodosum
Leprosy
medicine
Humans
Physical Examination
General Environmental Science
Erythema nodosum
Lepromatous leprosy
Clinical Trials as Topic
integumentary system
business.industry
Incidence (epidemiology)
Body Weight
General Engineering
Infant, Newborn
Drug Resistance, Microbial
General Medicine
Papers and Originals
medicine.disease
Dermatology
Clinical trial
Immunology
Costs and Cost Analysis
General Earth and Planetary Sciences
Phenazines
business
medicine.drug
- Language
- English
A comparison of clofazimine and dapsone in the management of untreated lepromatous leprosy showed no significant differences between the two drugs in terms of morphological and bacterial indices. The incidence of erythema nodosum leprosum was similar in the two groups. Since dapsone is cheaper than clofazimine it remains the drug of choice for the routine management of untreated lepromatous leprosy.