Comparison of guidelines for diagnosing suspected stable angina and the additional value of the calcium score
- Resource Type
- Authors
- Dirkjan Kuijpers; Jaap W. Deckers; Dorine Rijlaarsdam-Hermsen; Paul R. M. van Dijkman; Ron T. van Domburg
- Source
- International Journal of Cardiology, 344, 1-7. Elsevier Ireland Ltd
- Subject
- Male
medicine.medical_specialty
Nice
Coronary Artery Disease
Chest pain
Coronary Angiography
Stable angina
Risk Assessment
Coronary artery disease
Predictive Value of Tests
Risk Factors
Internal medicine
medicine
Humans
In patient
cardiovascular diseases
Angina, Stable
Prospective Studies
computer.programming_language
business.industry
Diagnostic algorithms
Middle Aged
medicine.disease
United States
medicine.anatomical_structure
Cardiology
Calcium
Female
medicine.symptom
Cardiology and Cardiovascular Medicine
business
computer
Calcium score
Artery
- Language
- ISSN
- 1874-1754
0167-5273
Background The performance of current diagnostic algorithms of the American College of Cardiology/American Heart Association (ACC/AHA), National Institute for Health and Care Excellence (NICE) and European Society of Cardiology (ESC) in patients with stable chest pain and coronary artery calcium (CAC) remains a matter of debate. We compared their merits in patients with CAC and investigated the additional value of the CAC score to improve diagnostic accuracy and risk stratification. Methods and results Patient data were obtained from a prospective registry of 642 consecutive patients. Mean age 63 (SD 11) years, 50% male. According to the guidelines, low and intermediate/high pre-test probability groups were constructed. Patients were reclassified based on their CAC score. Obstructive coronary artery disease (CAD) was observed in 14%. All models performed modestly in accurately predicting CAD (c-statistic