PDF file - 328K, Scheme 1. Synthesis of YNH motif and dYNH motif Scheme S2. Synthetic route for YSA-PTX Figure S1. In vivo prostate cancer xenograft studies. Figure S2. EphA2 expression in RENCA renal carcinoma cells and PC3M prostate cancer cells. Supplemental Table 1. Athymic nude mice bearing pre-established subcutaneous PC3M tumors (230 mm3 average volume) were treated three times weekly for a period of 18 days (8 total injections) with intravenous doses of vehicle (CT), PTX (10 mg/Kg) and DYP-PTX or YSA-PTX (at a dose equimolar to the taxol dose).