A major concern in the transportation sector is that of road accidents and fatalities occurring due to driver fatigue. In this study, we have developed tin-coated copper active electrodes embedded onto the vehicle seat cover that can ubiquitously measure driver cardiac parameters. The proposed cECG sensor system was evaluated with conventional ECG system in static and dynamic real-time driving scenarios. Experimental results from filtering and R peak detection show an improved determination coefficient higher than 98% for highways driving conditions and 93.7% for city driving conditions when compared to conventional ECG measurements. The decrease in cECG signal detection for city driving could be attributed to frequent upper body movements required for steering, gear shifting, and braking in city traffic as compared to highways. This is evident from the improvement in R peak detection accuracy for cECG measurements from the passenger’s seat when compared to the driver’s seat. Since the number of fatalities due to road traffic accidents are biased on highways than on city roads, the developed cECG system would be ideal for long-term driver health and fatigue monitoring with high accuracy.