Anisocytosis predicts postoperative renal replacement therapy in patients undergoing heart valve surgery
- Resource Type
- Authors
- Mariusz Kuśmierczyk; Piotr Duchnowski; Piotr Szymański; Tomasz Hryniewiecki
- Source
- Cardiol J
- Subject
- medicine.medical_specialty
Multivariate analysis
medicine.medical_treatment
Clinical Cardiology
030204 cardiovascular system & hematology
urologic and male genital diseases
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Risk Factors
Internal medicine
medicine
Clinical endpoint
Humans
Postoperative Period
Prospective Studies
Renal replacement therapy
Cardiac Surgical Procedures
Prospective cohort study
medicine.diagnostic_test
business.industry
Acute kidney injury
Complete blood count
Red blood cell distribution width
General Medicine
medicine.disease
Heart Valves
female genital diseases and pregnancy complications
Renal Replacement Therapy
Cardiology
Anisocytosis
Cardiology and Cardiovascular Medicine
business
- Language
- ISSN
- 1898-018X
1897-5593
Background: Acute kidney injury (AKI) is one of the serious postoperative complications in patients undergoing heart valve surgery. The aim of the present study was to identify selected biomarkers to predict AKI requiring renal replacement. Methods: A prospective study was conducted on a group of 751 patients undergoing heart valve surgery. The data on risk factors, preoperative complete blood count, course of operations and postoperative period was assessed. The primary endpoint at the 30-day follow-up was postoperative AKI requiring renal replacement therapy. The secondary end-point was death from all causes in patients with postoperative AKI requiring renal replacement. Results: The primary endpoint occurred in 46 patients. At multivariate analysis: age, red cell distribution width (RDW) and C-reactive protein remained independent predictors of the primary endpoint. Hemoglobin and RDW were associated with an increased risk of death. Conclusions: Elevated RDW is associated with a higher risk of postoperative AKI and death in patients with AKI.