A Whole-Body Physiologically Based Pharmacokinetic Model for Alpha Particle Emitting Bismuth in Rats
- Resource Type
- Authors
- Ambros J. Beer; Gerhard Glatting; Nouran Zaid; Gordon Winter; Peter Kletting
- Source
- Cancer Biotherapy and Radiopharmaceuticals. 37:41-46
- Subject
- 0301 basic medicine
Cancer Research
chemistry.chemical_element
Models, Biological
Bismuth
Mice
03 medical and health sciences
0302 clinical medicine
Pharmacokinetics
Animals
Tissue Distribution
Radiology, Nuclear Medicine and imaging
Decay product
Pharmacology
Radiochemistry
General Medicine
Alpha particle
Alpha Particles
Rats
030104 developmental biology
Liver
Oncology
chemistry
030220 oncology & carcinogenesis
Whole body
α particles
- Language
- ISSN
- 1557-8852
1084-9785
Introduction/Aim: α particle emitting bismuth (212Bi) as decay product of 212Pb-labeled pharmaceuticals has been effective in targeted α particle therapy (TAT). Estimating the contribution of 212Bi...