Fertility in a male with trisomy 21
- Resource Type
- Authors
- Martin Bobrow; Richard Sheridan; A Cawood; P Debenham; J. Llerena; S Matkins
- Source
- Journal of medical genetics. 26(5)
- Subject
- Adult
Male
medicine.medical_specialty
Down syndrome
media_common.quotation_subject
Aneuploidy
Chorionic villus sampling
Fertility
Paternity
Biology
Genetics
medicine
Humans
Genetics (clinical)
media_common
Pregnancy
medicine.diagnostic_test
Obstetrics
Mosaicism
Karyotype
DNA
medicine.disease
Reproduction
Down Syndrome
Trisomy
Polymorphism, Restriction Fragment Length
Research Article
- Language
- ISSN
- 0022-2593
We review the published reports on reproduction in cases of non-mosaic trisomy 21 (Down's syndrome) and present the first fully documented case of a non-mosaic male with Down's syndrome fathering a pregnancy, a fact which has important implications in the light of caring for these people in the community.