Generalized pustular figurate erythema first report in two COVID‐19 patients on hydroxychloroquine
- Resource Type
- Authors
- P A Cerro; A M Morales-Callaghan; A M Palma-Ruiz; I Abadías-Granado; M C Gómez-Mateo; Yolanda Gilaberte; Robert A. Schwartz
- Source
- Journal of the European Academy of Dermatology and Venereology
- Subject
- medicine.medical_specialty
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
business.industry
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Hydroxychloroquine
Dermatology
medicine.disease
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Infectious Diseases
030220 oncology & carcinogenesis
medicine
Figurate erythema
Drug reaction
business
Generalized pustular
medicine.drug
- Language
- ISSN
- 1468-3083
0926-9959
Generalized pustular figurate erythema (GPFE) is a distinctive severe cutaneous drug reaction with widespread urticarial or edematous plaques scattered over the entire body that become topped with non-follicular pustules that evolve into erythematous and sometimes atypical targetoid plaques converging into annular and arcuate patterns prominent on the trunk and extremities (1). It has been linked with medications, especially hydroxychloroquine. We describe two COVID-19 patients on hydroxychloroquine who developed this eruption 2 and 3 weeks after the onset of hydroxychloroquine. This report is the first to our knowledge of COVID-19 patients on hydroxychloroquine developing GPFE.