Changes that are made in education during last decade is the guarantee of Georgia’s integration in the European educational space. Accordingly, medical education must be based on the international standards and must be result oriented to get the competitive graduates on the medical market. Within the new medical educational program “Medicine + PBL” a new Problem Based Learning (PBL) teaching method has been implemented on the faculty of Medicine at Akaki Tsereteli State University (ATSU) during 3 years. The innovations are the basic medical and clinical disciplines that are integrated in the program, also their supporting courses and social disciplines. The structure of the program is conditionally divided into three steps: teaching basic, preclinical and clinical subjects and clinical teaching and clinical practicing stages. Medical Doctor (MD) program is a “hybrid” program, where so called PBL cases are integrated into medical disciplines. In order to reach the learning outcomes, which includes the development of knowledge, practical skills/habits and values, the program is based on “4 spiral” model: the progress of knowledge and awareness, the doctor-patient communication, "public and population health" and "personal and professional growth". PBL teaching method and format strengthens the quality of program integration and provides the Medical Doctor with possibilities of effective achievement of Learning Outcomes (LOs).