A Case Report of False Positive FDG- PET/CT Mediastinal Lymph Node in Oesophageal Adenocarcinoma Revealed to be an Anthracotic and Anthracosilicotic Spindle Cell Pseudotumor (AASCP)
- Resource Type
- Authors
- Bannoura S; Hallal A; Andrew Barakat; Mohamad Haidar; Nina S. Shabb; Ghanem Aa; Mohamad Yasser R. Dergham; Mario Jreige
- Source
- Journal of Nuclear Medicine & Radiation Therapy.
- Subject
- Pathology
medicine.medical_specialty
PET-CT
medicine.diagnostic_test
Mediastinal lymphadenopathy
business.industry
medicine.disease
030210 environmental & occupational health
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
medicine.anatomical_structure
Fine-needle aspiration
Mediastinal lymph node
Biopsy
Medicine
Lymph
Radiology
business
Lymph node
Histiocyte
- Language
- ISSN
- 2155-9619
Anthracotic and anthracosilicotic spindle cell proliferation (AASCP) is a rare reactive proliferative entity of phagocytic histiocytes which can affect hilar and mediastinal lymph nodes. Fluorodeoxyglucose-positron emission tomography (FDG-PET) has been used for the clinical diagnosis and staging of oesophageal adenocarcinoma. We report the first case of AASCP exhibiting false positivity on FDG-PET imaging. A 76-year-old man with distal esophageal adenocarcinoma underwent PET/CT for staging revealing a positive mediastinal lymph node involvement. The patient underwent Endobronchial Ultrasound Fine Needle Aspiration Biopsy (EBUS-FNA) followed by an oesophagectomy with lymph node dissection. The histological diagnosis of the mediastinal lymphadenopathy was AASCP. In mediastinal lymph nodes of esophageal adenocarcinoma, AASCP could be a cause of false-positivity on FDG-PET imaging.