The roles of the caregiver, the healthcare professional, and the healthcare system are critical in order to maximize the potential of this relationship and minimize the harm which results when this fails. In doing so, an understanding of the challenges associated with caring, its knock-on effect on caregivers’ well-being, and situations that cause this to decline are examined. By understanding the factors that detrimentally affect the caregiver’s well-being, the concept of increasing resilience in the lives of these individuals leading to their empowerment is highlighted. Ultimately, the aim for this attention is to bring about improvements in the quality of life and well-being of people with dementia by enabling healthcare professionals to work effectively in partnership with fully empowered caregivers.