Pre-operative MRI staging of endometrial cancer in a multicentre cancer network: can we match single centre study results?
- Resource Type
- Authors
- V Stewart; A Ferri; Neil Soneji; N Bharwani; Andrea Rockall
- Source
- European radiology. 28(11)
- Subject
- Adult
medicine.medical_specialty
Referral
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
Neoplasm Invasiveness
Stage (cooking)
Neuroradiology
Cancer staging
Aged
Neoplasm Staging
Retrospective Studies
Aged, 80 and over
medicine.diagnostic_test
business.industry
Endometrial cancer
Cancer
Reproducibility of Results
Interventional radiology
Magnetic resonance imaging
General Medicine
Middle Aged
medicine.disease
Magnetic Resonance Imaging
Endometrial Neoplasms
030220 oncology & carcinogenesis
Preoperative Period
Myometrium
Female
Radiology
business
- Language
- ISSN
- 1432-1084
To evaluate the staging accuracy of magnetic resonance imaging (MRI) for endometrial cancer in daily practice over a 3-year period at a tertiary referral centre receiving scans from a large number of hospitals with varying protocols. To compare these daily practice results to published data from single-centre studies. After ethical approval, MRI staging records for 270 studies from nine network and three centre hospitals were retrospectively collected and compared with final operative histopathology. The International Federation of Gynaecology and Obstetrics (FIGO) stage, depth of invasion assessment and cervical stromal invasion were analysed and reasons for discrepancies reviewed. MRI-based complete FIGO stage was fully concordant with histopathology in 65.6%. MRI accuracy for depth of myometrial invasion and cervical stromal invasion was 73.3% and 89.3% respectively. Our results did not match the high accuracy previously reported in studies based on single centres. Published MRI staging accuracy from small single-centre studies were not replicated in a tertiary referral centre receiving scans with heterogeneous protocols over a 3-year period. These results highlight the challenges faced in daily practice and may reflect achievable and realistic MRI staging accuracies in large rapid throughput referral networks. Adherence to standardised high-quality protocols may help to improve future results. • Three-year MRI-staging accuracy for endometrial cancer in a multicentre cancer network • Daily practice MRI-staging accuracy did not meet results of single-centre studies • Large scale cancer network MRI-staging accuracies should be further evaluated • Treatment recommendations should be based on achievable MRI-staging accuracies