'Measuring the Impact of single dose of ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant) on hospital stay, ICU requirement, and mortality outcome in a tertiary care centre'
- Resource Type
- Authors
- Tushar Patel; Neeraj Bharti; Jigar Mehta; Ankita Jain; Dipesh Sorathiya; Adit Desai; Wasimahmed Sachora; Kalpesh Sukhwani; Parth Desai; Anuja Desai; Parin Mehta; Vivek Nanda
- Source
- International Journal of Infectious Diseases
- Subject
- History
medicine.medical_specialty
COVID-19 Vaccines
Polymers and Plastics
Population
Tertiary care
Industrial and Manufacturing Engineering
Article
Tertiary Care Centers
Virus vaccine
Internal medicine
ChAdOx1 nCoV-19
Pandemic
medicine
Humans
Business and International Management
education
education.field_of_study
business.industry
SARS-CoV-2
Vaccination
COVID-19
Retrospective cohort study
Length of Stay
Intensive Care Units
Observational Studies as Topic
ChAdOx1 nCoV-19 vaccine
vaccine hesitancy
Observational study
SARS CoV-2 infection
business
Hospital stay
- Language
- English
- ISSN
- 1878-3511
1201-9712
Background: Control of the global COVID-19 pandemic will require mass vaccination especially in developing countries. To comparatively evaluate ICU requirement, length of stay and mortality between single dose vaccinated and non-vaccinated hospitalized COVID-19 patients. Methods: Retrospective, observational study from 1st April 2021 till 30th June 2021 carried out in a tertiary care hospital in Western Indian region. Single centre population-based study at a tertiary COVID care centre. 569 patients admitted with positive polymerase chain reaction tests for COVID-19 at our institute were enrolled in the study. 137 admitted patients with single dose of ChAdOx1 nCoV-19 vaccine were considered as Vaccinated patients as per case definition and 432 patients who have not received any dose of vaccine were considered as Non-vaccinated patients. Findings: Main outcomes were length of hospital stay including ward and ICU in both groups. Severity of SARS-CoV-2 infection was determined based on ventilator support and mortality. Of the 569 patients enrolled in the study based on the eligibility criteria, 137 (24.08%) patients had received a single dose of ChAdOx1 nCoV-19 vaccine while 432 (75.92%) patients had not received any form of vaccination. Overall length of stay in the hospital was similar for both groups however a significant difference was seen in length of stay in ward and ICU. Vaccinated patients were admitted for 6.21 ± 3.204 days in the ward while non-vaccinated patients were admitted for 5.56 ± 4.55 days (p