Small (∼1 mm) neon pellet fragments are fired into DIII-D H-mode plasmas, and resulting trajectory-averaged photon efficiencies (neutral neon ionization events for every photon emitted) of [Formula: see text] are estimated for Ne-I 640 nm by dividing the estimated initial pellet fragment mass by the measured number of emitted Ne-I photons. The experiments are modeled by running the Lagrangian particle (LP) fluid/magneto-hydrodynamic pellet code to estimate axial ablation plume neon density profiles and temperature profiles at each pellet position. These solutions are then fed into the PrismSPECT collisional-radiative code, which calculates resulting neon charge states and photon emission rates, giving a profile-average of [Formula: see text]. The burnthrough plasma minor radius predicted by LP ([Formula: see text]) is reasonably close to the experimental observation [Formula: see text]. The modeling indicates that local S/ XB is not constant along the pellet trajectory but tends to increase with increasing ablation rate. Non-equilibrium kinetics are predicted to be very important, while line trapping is predicted to be relatively unimportant (for Ne-I 640 nm S/ XB).