Patients with pheochromocytoma are typically symptomatic. Hypertension is the most common sign of pheochromocytoma. Clinically silent giant pheochromocytoma is a rare adrenal disease; complete resection is the only curative treatment. Due to the serious surgical risk, successful resection is very difficult. We report a case of 70-year-old- female with giant pheochromocytoma, which was successfully resected. There were no intraoperative and postoperative complications. We analyze and report our experience.