Association between hamstring coactivation during isokinetic quadriceps strength testing and knee cartilage worsening over 24 months
- Resource Type
- Authors
- Murphy, MT; Wang, N; Felson, DT; Nevitt, MC; Lewis, CE; Frey-Law, L; Guermazi, A; Segal, NA
- Source
- Osteoarthritis and cartilage, vol 30, iss 6
- Subject
- Male
Aging
Knee Joint
Epidemiology
Arthritis
Clinical Sciences
Biomedical Engineering
Hamstring Muscles
Human Movement and Sports Sciences
Middle Aged
Quadriceps Muscle
Arthritis & Rheumatology
Cartilage
Clinical Research
Musculoskeletal
Osteoarthritis
Humans
Knee
Female
Muscle activation
Articular
Aged
- Language
ObjectiveThis study aimed to determine longitudinal associations, including sex-specific differences, between greater knee flexor antagonist coactivation and worsening cartilage morphology in knees with or at risk for osteoarthritis (OA).DesignBaseline measurements were collected at the 60-month visit of a longitudinal osteoarthritis study following community-dwelling participants (MOST). Knee flexor and extensor muscle activity were measured with surface electromyography during a maximal isokinetic knee extension task. MRI analyzed knee cartilage morphology at baseline and 24-month follow-up. Multivariable adjusted logistic regression models were used to assess associations between coactivation level and cartilage morphology worsening.ResultsAnalysis of 373 women (mean±SD age 67.4±7.3 years and BMI 29.7±5.0kg/m2) and 240 men (66.5±7.8 years and 29.9±4.5kg/m2) revealed that women had greater medial (P