Rafflesia mixta Barcelona, Manting, Arbolonio, Caballero & Pelser is described as a new species from the Caraga Region of northeastern Mindanao, Philippines. In their general morphology, the flowers of this species most closely resemble those of R. mira, but they are different in details of the perigone warts and processes, disk color, and relative size of the diaphragm opening. This discovery brings the total number of Philippine Rafflesia species to twelve, of which four are found on the island of Mindanao.