Additional file 1 of Assessing the impacts of COVID-19 vaccination programme’s timing and speed on health benefits, cost-effectiveness, and relative affordability in 27 African countries
- Resource Type
- Authors
- Liu, Yang; Procter, Simon R.; Pearson, Carl A. B.; Montero, Andrés Madriz; Torres-Rueda, Sergio; Asfaw, Elias; Uzochukwu, Benjamin; Drake, Tom; Bergren, Eleanor; Eggo, Rosalind M.; Ruiz, Francis; Ndembi, Nicaise; Nonvignon, Justice; Jit, Mark; Vassall, Anna
- Source
- Subject
- Language
Additional file 1: Supplemental Figures: Figure S1. Vaccine roll-out trajectories by age group. Figure S2. Diagram of Transmission Model Structure. Figure S3. Countries included and excluded from this analysis. Figure S4-6. Performance of model fitting process, Part 1-3 (in alphabetical order). Figure S7. Fitted parameters. Figure S8-10. Health Outcomes Associated with Vaccine Roll-out Scenarios (by vaccine type and by health outcome). Figure S11. The association between the proportion of DALYs averted attributable to older adults and the performance of medium and fast scenarios. Figure S11. Effect sizes estimated in the multivariable regression model linking country characteristics to ICERs as proportions of GDP per capita. Figure S12. Target vaccine price under different perceived cost-effectiveness thresholds. Supplemental Tables: Table S1. Model Equations. Table S2. Epidemic and Healthcare Process Parameters. Table S3. Additional Data Sources. Table S4. Other vaccine and vaccination programme characteristics. Table S5. Variants of Concern Introduction. Table S6. List of countries with fitted models. Table S7. Itemised cost per dose per activity for base countries - viral vector / AstraZeneca-like vaccine. Table S8. Itemised Cost per dose per activity for base countries - mRNA / Pfizer-like vaccine. Table S9. Cost per dose for countries with fitted models. Table S10. CHEERS 2022 Checklist. Supplemental Methods: Methods S1. Further Model Descriptions. Methods S2. Fitting Process. Methods S3. Characterising behavioural change using data on non-pharmaceutical intervention and mobility. Methods S4. Calculating COVID-19 severe, critical, and death cases. Methods S5. Lengths of Stay (LoSs). Methods S6. Calculating Disability-adjusted Life Years (DALYs). Methods S7. Estimating Vaccine Delivery Costs. Methods S8. Extrapolating unit costs from base countries to other countries in Africa. Methods S9. Extrapolating vaccine unit costs for different roll-out scenarios. Methods S10. ICERs and Proportions of DALYs averted by those above 60 years.