Objective: The purpose of this analysis was to examine quality of life and dissociation in anxiety disorder subjects with histories of trauma, some of whom met criteria for posttraumatic stress disorder (PTSD). Method: Subjects came from a prospective, longitudinal study ofanxiety disorders. Information was gathered on role, sociallife, suicide attempts, psychiatric hospitalization, alcohol and substance abuse, depression, and dissociation. Results: Subjects with PTSD had the worst functioning on all ofthe measures examined except social life. Those with histories of trauma but no PTSD differed from subjects who reported no history of trauma, primarily in high rates ofalcoholism and minor depression. Conclusions: PTSD has severe effects on quality of life in virtually all spheres of life. The high levels of depression, suicide attempts or gestures, and alcoholabuse are ofparticular concern and show that trauma can have long-lasting effects. (Am JPsychiatry1993;150:1512-1516)