Imaging spectrum of acute invasive fungal rhino-orbital-cerebral sinusitis in COVID-19 patients: A case series and a review of literature
- Resource Type
- Authors
- Tougan Taha Abdelaziz; Mohammad S. Mahmoud; Doaa Maamoun Ashour; Mohamed Ibrahim Saleh; M. M. M. Ashour; Anas Askoura
- Source
- Journal of Neuroradiology
- Subject
- Pediatrics
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
RT-PCR, reverse transcriptase-polymerase chain reaction
030218 nuclear medicine & medical imaging
03 medical and health sciences
High morbidity
0302 clinical medicine
DM, diabetes mellitus
medicine
Mucormycosis
Humans
Radiology, Nuclear Medicine and imaging
In patient
Sinusitis
ComputingMethodologies_COMPUTERGRAPHICS
COVID-19, coronavirus disease 2019
Acute invasive fungal rhino-orbital-cerebral sinusitis
Radiological and Ultrasound Technology
SARS-CoV-2
business.industry
Mortality rate
Incidence (epidemiology)
COVID-19
AIFS, acute invasive fungal rhino-orbital-cerebral sinusitis
medicine.disease
PL, perception of light
Cohort
DCL, disturbed conscious level
Original Article
Neurology (clinical)
Tomography, X-Ray Computed
business
030217 neurology & neurosurgery
- Language
- ISSN
- 0150-9861
Graphical abstract
Background The incidence of devastating opportunistic coinfections in patients with COVID-19 infection, their imaging features and their morbidity and mortality consequences need to be unraveled. Methods This is a case series presenting the radiologic features and clinical presentation of acute invasive fungal rhino-orbital-cerebral sinusitis (AIFS) in eight hospitalized patients with confirmed COVID-19 infection. Results Our patient cohort presented with symptoms of the invasive fungal disease within 12–35 days from their initial presentation with COVID-19 infection. The cross-sectional imaging features of AIFS associated with COVID-19 infection do not differ from those reported in the literature for AIFS associated with other risk factors, yet our patients had features of aggressive late-stage forms with high morbidity and mortality rate. Conclusion AIFS is a possible encounter in patients with COVID-19 patients and radiologists should be familiar with its imaging features.